A New Guideline on Cardiovascular–Kidney–Metabolic Syndrome

Clinical Takeaway

: Obesity, diabetes, chronic kidney disease, and cardiovascular disease are all part of the new syndrome and should be managed within a unified framework.

An overview of the 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular–Kidney–Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Background

The American College of Cardiology and American Heart Association have released a comprehensive guideline focused on the concept of cardiovascular–kidney–metabolic (CKM) syndrome. The syndrome is defined as a systemic disorder characterized by interactions among obesity, type 2 diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD).

Key Points

CKM syndrome is classified into four stages:
- Stage 1 — Overweight, obesity, or prediabetes
- Stage 2 — Hyper…

Reviewing Author

Sarah E. Post, M.D.

Disclosures

Nothing to disclose