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Chronic subdural hematomas (cSDH) are the most common reason for neurosurgical intervention in elderly patients, who commonly also have cardiovascular comorbidities and aspirin use. At present, neurosurgeons routinely withhold aspirin from these patients during the perioperative period, but evidence is scant regarding this strategy’s relative risks and benefits. In a randomized study, 155 patients with cSDH (mean age, 78) who were taking aspirin and were to undergo burr hole drainage at neurosurgical centers received either low-dose aspirin (100 mg) or placebo for 12 days, after which all patients resumed aspirin treatment. Only 130 patients completed the 6-month follow-up; the others withdrew consent, died, or were lost to follow-up…