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A new report provides details about two premature infants (26 and 33 weeks’ gestation) from different states in the United States. At 2 months and 5 weeks of age, respectively, these infants developed sepsis and extensive meningoencephalitis due to Paenibacillus dendritiformis, a gram-positive bacterium found in the environment. Researchers initially identified the organism as Paenibacillus thiaminolyticus using routine microbiology techniques but later identified it as P. dendritiformis using whole-genome sequencing.
Both infants had severe neurologic sequelae with intracranial abscesses, leading to hydrocephalus in one infant and death in the other.
Neither infant had any identifiable risk factors, and risk factors identif…