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Candidozyma auris, a multidrug-resistant fungal pathogen formerly known as Candida auris, tends to colonize patients in high-acuity, long-term-care settings, and mortality from invasive disease is as high as 45%. A clinical score to identify which colonized patients are most likely to develop invasive disease could improve management and prevention strategies.
In a previous retrospective study of patients in Spain colonized with C. auris, researchers identified multiple factors associated with invasive disease. Now, the researchers have validated those findings in a separate cohort from two Spanish ICUs and created a risk-stratification score.
Of 216 colonized patients in the validation cohort, 14% developed C. auris fungemi…