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Acute bronchitis is one of the most commonly diagnosed diseases in the emergency department and is the cause of more than 10 million doctor visits every year. Most patients are prescribed antibiotics, despite concerns about growing antibiotic resistance and substantial evidence that antibiotics are ineffective for treating bronchitis. These authors evaluated the effectiveness of azithromycin for treating bronchitis in a multicenter, randomized, double-blind study.
Of 448 patients assessed for possible bronchitis (productive or nonproductive cough lasting for 2-14 days without evidence of pneumonia), 340 were diagnosed with bronchitis, and 220 met the criteria for randomization. Of the 189 patients who completed the study, 97 received 250 mg/…