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Many scoring systems are used to assess the severity of illness or risk for death in critically ill or injured patients, including the Acute Physiology and Chronic Health Evaluation (APACHE), APACHE II, APACHE III, Simplified Acute Physiology Score, and Sepsis-related Organ Failure Assessment. However, these systems were not designed to aid clinical decision making, and they usually require more information than is typically available in the emergency department. In this prospective study of consecutive adult ED patients at risk for infection who were admitted, investigators identified significant correlates of death and developed a clinical prediction rule to stratify patients by risk for death at 28 days.
Of 3179 patients, 2070 were random…