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Use of neuramidase inhibitors has grown recently because of increases in both the incidence of influenza B and the resistance of influenza A to hemagglutinin inhibitors. Researchers in Japan assessed the effectiveness of the neuramidase inhibitor oseltamivir for treating influenza A and influenza B in children.
In an observational study, patients aged 1 to 15 years who presented with fever of less than 48 hours’ duration underwent rapid testing for influenza typing before being treated with weight-appropriate doses of oseltamivir. The main outcome measure was the duration of fever in the 127 children with influenza A (mean age, 7.0 years) and the 362 children with influenza B (mean age, 5.2 years).
Duration of fever was significantly longer i…