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For prevention of wound infections, irrigation is more effective than cleaning with antibacterial solutions, and the use of sterile saline for irrigation is the current standard of care. In a multicenter prospective trial, researchers compared wound infection rates in 715 adult patients with simple lacerations who were randomized to either clinician-administered sterile saline irrigation or at least 2 minutes of self-administered tap-water irrigation after adequate wound anesthesia. Wounds were closed with sutures or staples at the discretion of the treating physician. Patients did not receive antibiotics.
Among the 88% of patients who were available for follow-up by return emergency department visit or by telephone, rates of wound infection…