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Both dyspnea and exacerbations of congestive heart failure are common complaints in emergency medicine practice. Determining which dyspneic patients have congestive heart failure and which do not is a challenge. Researchers reviewed data from the PRIDE (ProBNP Investigation of Dyspnea in the Emergency Department) study to determine the role of natriuretic peptide (NT-proBNP) testing in making this distinction.
After a standard clinical evaluation of a patient with dyspnea, the treating clinician, who had access to all standard diagnostic tests available (but not proBNP level), was asked to estimate from 0% to 100% the likelihood that the patient had acute decompensated heart failure (ADHF). Estimates of ≥80% or ≤20% were considered to reflec…