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Patients with clinical states other than acute coronary syndromes (ACS) often have elevated troponin levels, but the association between troponin elevation and outcomes in these patients is unknown. Using data from the 105,000 hospitalized patients in the Acute Decompensated Heart Failure National Registry (ADHERE), investigators assessed this association in 68,000 patients with acute decompensated heart failure who had troponin I or T measured within 24 hours after admission and had serum creatinine levels ≤2.0 mg/dL.
Overall, 6.2% of patients had a positive troponin level (defined as ≥1.0 μg/L for troponin I and ≥0.1 μg/L for troponin T). The primary outcome was all-cause in-hospital mortality; secondary outcomes included length of stay an…