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In patients who present with chest pain, ST-segment changes are strongly associated with acute coronary syndromes (ACS) and risk for cardiovascular events. These authors evaluated the association between T-wave changes and risk for adverse cardiovascular events at 30 days in 5582 patients (age, >30) who presented to a single emergency department with a chief complaint of chest pain and had an electrocardiogram ordered in the ED. Investigators reviewed patients’ hospital courses and followed-up with patients by telephone calls 30 days after presentation.
Overall, 25% of patients had T-wave abnormalities (flattening or any degree of inversion) on the initial ECG. T-wave changes were associated with increased risk for the composite endpoint of …