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Antibiotics frequently are prescribed unnecessarily for patients with nonspecific lower respiratory tract infections despite overwhelming evidence against the practice. In a cluster-randomized controlled trial, researchers assessed the effects of enhanced physician–patient communication skills training (tailored to address patients’ concerns about the need for antibiotics) and use of point-of-care C-reactive protein (CRP) testing on antibiotic prescribing for adult patients with lower respiratory tract infections. Forty general practitioners at 20 general practices in the Netherlands were allocated to communications skills training (84 patients), CRP testing (110 patients), both interventions (117 patients), or usual care (control group; 12…