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In two recent studies, researchers retrospectively reviewed charts of patients with discharge diagnoses of community-acquired pneumonia (CAP) to assess concordance of initial antibiotic regimens with the 2007 joint guideline from the Infectious Diseases Society of America and the American Thoracic Society (see table) and to determine if concordant-therapy improves outcomes.
McCabe and colleagues reviewed charts of nearly 55,000 non–intensive care unit patients aged 18 and older (mean, 71) at 113 hospitals in the U.S. Sixty-five percent of patients received guideline-concordant therapy, and these patients had a significantly lower risk for in-hospital death than those who received nonconcordant therapy (odds ratio, 0.70), along with shorter l…
