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Human parvovirus B19 is associated with erythema infectiosum (fifth disease) and, rarely, with sporadic purpuric or petechial rashes, typically in a focal sock-and-glove distribution. To describe clinical and laboratory features associated with parvoviral-induced petechial rashes, investigators prospectively studied children who presented with petechial rashes during a parvovirus B19 outbreak in Madison, Wisconsin, in 2007.
Of 17 children with petechial rashes, 13 (median age, 7 years) had confirmed parvovirus B19 infections. Eleven patients with confirmed infection presented with fever. The most commonly associated complaints were headache (8 patients), sore throat (5), and fatigue (4). Most patients appeared well; only four were described …