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In a prospective cohort study at a single Canadian emergency department, researchers assessed sex differences in presentation of chest pain in 970 hemodynamically stable adult patients (40% women; mean age, 60) with low-to-moderate risk for acute coronary syndrome (ACS) and no history of cocaine use.
Women were significantly more likely than men to have low (<10%) pretest probability for ACS (85% vs. 76%) and were significantly less likely than men to have known coronary artery disease (21% vs. 34%), pain characteristics typical for ACS (37% vs. 46%), positive stress test results for cardiac ischemia (4% vs. 8%), and acute myocardial infarction within 30 days (5% vs. 8%). Although women were less likely than men to undergo angiography (9% vs…