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In a prospective observational study, investigators developed a decision rule for diagnosis of intussusception based on clinical and radiographic findings in 310 children (age range, 1 month to 6 years) who presented to a pediatric emergency department in the U.S. with clinically suspected intussusception. Patients who had histories of intussusception, abdominal surgery, or gastrointestinal disorders were excluded. Providers recorded selected historical and clinical findings before radiologic studies. On the basis of final radiology reports, plain radiographs were classified as positive (e.g., small bowel obstruction, target or crescent sign), possible positive (e.g., abnormal gas pattern, air fluid levels, dilated intestinal loops), or neg…