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Investigators retrospectively assessed the prevalence and clinical significance of prolonged QTc values (≥440 milliseconds) in 403 patients (age range, 0–22 years; mean age, 17 years) who presented to a pediatric emergency department (ED) during 1 year and for whom an electrocardiogram (ECG) was obtained. Patients were excluded if they had congenital heart disease, arrhythmias, electrolyte abnormalities, or exposure to QT interval-prolonging medications.
Indications for ECGs were chest pain (115 patients), syncope (104), ingestions or overdose (52), psychiatric or neurological complaints (39), abdominal pain (21), palpitations, (20), and “other” (52). QTc intervals ranged from 344–566 milliseconds; 131 patients (33%) had QTc intervals >440 m…