OTC Topical Pain Relievers Pose Burn Risk

Over-the-counter topical muscle and joint pain relievers containing capsaicin, methyl salicylate, or menthol (e.g., Bengay, Icy Hot) may cause serious chemical burns, according to the FDA.

A review of two adverse drug event databases, as well as the medical literature, found 43 reports of burns linked to these products. Those containing menthol were the most likely to cause second- and third-degree burns.

The FDA advises clinicians to warn patients about the burn risk and to provide guidance on using the products appropriately. In particular, the pain relievers should not be applied to broken or damaged skin; the area should not be bandaged tightly; and heating pads should not be used.

Adverse events linked to these pain relievers should be reported to the FDA's MedWatch program, the agency says.