Gram-Negative Antibiotic Resistance: News from the Front

Successful treatment of gram-negative bacteremia is being challenged by increasing antibiotic resistance, the extent of which varies by region. Ongoing monitoring of these trends in . . .

Successful treatment of gram-negative bacteremia is being challenged by increasing antibiotic resistance, the extent of which varies by region. Ongoing monitoring of these trends in the U.S., Canada, and Latin America is performed through a multi-center surveillance system (SENTRY) using all bacteremic isolates from a network of sentinel hospitals throughout the region.

During 1997, 4,267 gram-negative bloodstream infections (evenly distributed between nosocomial and community-acquired infections) were analyzed. More than three quarters of the gram-negative isolates were Escherichia coli (41%), klebsiella species (17.9%), Pseudomonas aeruginosa (10.6%), or enterobacter species (9.4%). Most E. coli isolates were community-acquired, whereas mo…

Reviewing Author

B Britigan