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Effective TB treatment depends on patients completing a full course of therapy. Ensuring adherence can be a daunting challenge in resource-poor nations. In recent years, researchers have published several reports of novel approaches to TB therapy in developing countries; now, a multinational team of investigators has described the evaluation of a new strategy in Senegal.
Sixteen district health centers (DHCs) were randomized to provide either standard therapy following national TB treatment recommendations or enhanced care that included (1) increased counseling and communication between healthcare personnel and patients, (2) decentralization of treatment to locations closer to patients, (3) patient selection of a directly observed therapy su…