Treatment of Aspergillosis

Target Population: Infectious diseases specialists

Type: Consensus statement

Background: Aspergillosis has become an important cause of life-threatening infection among immunosuppressed patients, especially lung, combined heart/lung, and allogeneic hematopoietic stem-cell transplant recipients. In such patients, aspergillosis presents often as an angioinvasive pulmonary process and occasionally as a sinonasal infection; infection can also disseminate to the central nervous system and other extrapulmonary sites. Even with antifungal therapy, mortality can be high. Outcomes are much better in patients with noninvasive disease (e.g., allergic bronchopulmonary aspergillosis or …