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Approximately 5% of hepatitis B vaccine recipients do not generate antibodies to hepatitis B surface antigen (anti-HBs) at a protective level (≥10 mIU/mL). Several strategies to induce protective immunity among these “nonresponders” have been tested, with varying success. Investigators in Sweden recently assessed the effectiveness of the combined hepatitis A/B vaccine in 64 adults — 44 nonresponders who had not developed protective anti-HBs levels after ≥4 intradermal doses of the Engerix-B recombinant hepatitis B vaccine and 20 control participants who were not immune to hepatitis B virus (HBV) or hepatitis A virus (HAV) and had never received the hepatitis B vaccine. All participants received 2 mL of combined hepatitis A/B vaccine at 0, 1…