Treatment of HIV Infection: Updated Guidelines from the IAS–USA

The panel recommends that HIV-infected patients with CD4 counts <350 cells/mm³ be treated and that therapy be considered in patients with higher CD4 counts.

Target Population: Physicians and other caregivers who treat adults with HIV infection

Sponsoring Organization: International AIDS Society–USA

Type: Evidence-based consensus guidelines using a categoric rating system

Key Points: This document updates guidelines that were last revised in 2006. The new guidelines recommend that symptomatic patients, and asymptomatic patients with CD4 counts <350 cells/mm³, receive antiretroviral therapy (ART). In addition, based on evidence of increased risk for non–AIDS-defining conditions (e.g., cardiovascular, renal, or hepatic disease; non–AIDS-related cancers) in HIV-infected persons, therapy should be considered for patients who have CD4 counts >350 cells/mm³, especially if they have comorbidities or r…

Reviewing Author

Rajesh T. Gandhi, MD

Disclosures

Grant/Research SupportNIH

Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)

Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)