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Because susceptibility testing of anaerobes is not routinely performed, data from surveillance studies are important in guiding antibiotic selection. Investigators in Taiwan recently conducted a surveillance study on clinical isolates of commonly encountered anaerobes, collected from 2000 through 2007, and on Bacteroides fragilis isolates associated with nosocomial infections, collected from 1990 through 2006. Bacteremia-associated isolates from 2006 were also evaluated.
Overall, susceptibilities to ampicillin-sulbactam, cefmetazole, and clindamycin decreased during the study period. Metronidazole, piperacillin-tazobactam, carbapenems, and chloramphenicol generally retained good activity against isolates of common anaerobes, although some tr…