The likelihood of such clearance was associated with geographic origin, HBV status, and risk behavior.
About two thirds of people exposed to hepatitis C virus (HCV) develop chronic viremia. Although several factors (e.g., female sex, symptomatic infection, nonblack race) have been associated with HCV clearance in people without HIV infection, less is known about predictors of spontaneous resolution in HIV-infected individuals. To examine this issue, investigators conducted a study involving HIV-infected, HCV antibody–positive patients in the large EuroSIDA cohort.
Of 1940 HCV antibody–positive patients with stored samples available, 1496 (77%) were found to have evidence of chronic viremia, as determined by HCV RNA positivity, known HCV genotype, or both. A multivariable analysis revealed that spontaneous HCV clearance was significantly more …
Reviewing Author
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)