Antibiotic Resistance of E. coli in College Students with UTIs

Nitrofurantoin should be considered a first-line empirical treatment.

The Infectious Diseases Society of America treatment guidelines for uncomplicated urinary tract infections (UTIs) in women position trimethoprim-sulfamethoxazole (TMP-SMX) as the first-line treatment but caution against its empirical use if local Escherichia coli resistance rates are ≥20%. Recently, this threshold has been reached in some areas. Additionally, increased use of quinolones has led to escalating resistance to these agents. A new study from Duke University sheds light on E. coli resistance rates in young women.

Records of 167 college women presenting to a student health clinic between 2005 and 2007 with symptoms of UTI and cultures positive for E. coli were retrospectively reviewed. Antibiotic susceptibilities of the women’s isol…

Reviewing Author

Lynn L. Estes, PharmD

Disclosures

Editorial boardsMayo Clinic Antimicrobial Therapy Quick Guide

Lynn L. Estes, PharmD

Disclosures

Editorial boardsMayo Clinic Antimicrobial Therapy Quick Guide