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During seasonal influenza epidemics and previous pandemics, pregnancy has been associated with increased disease severity. For example, in a series of pregnant women with influenza reported during the 1918 pandemic, about half developed pneumonia, and of these women, more than half died. More recently, during the 1957 pandemic, half of the influenza-related deaths among women of reproductive age in Minnesota occurred during pregnancy. To assess the situation with the new H1N1 virus, the CDC implemented enhanced surveillance for H1N1 infections among pregnant women in the U.S.
From April 15 through May 18, 2009, 34 H1N1 cases (31 confirmed, 3 probable) from 13 states were reported in pregnant women. The women were aged 15 to 42 (median, 26); …