Typhoid Fever in the U.S.

Most cases of typhoid fever in the U.S. are associated with travel to the Indian subcontinent; drug-resistant organisms underlie an increasing proportion of such infections.

Although typhoid fever is now rare in the U.S., the proportion of cases caused by drug- resistant Salmonella typhi is increasing. CDC researchers recently analyzed national surveillance data for cases of typhoid fever diagnosed in the U.S. from 1999 through 2006 to assess patterns in risk factors and antimicrobial susceptibility.

During the study period, 1902 cases of typhoid fever were reported to the CDC; 51% of these cases were in California, New York, and New Jersey. For the 1830 cases with travel information available, 79% were travel associated; 67% of patients with travel-associated typhoid had visited India, Pakistan, or Bangladesh. Among the travelers who reported vaccination status, only 5% had received a typhoid vaccine during the…

Reviewing Author

Richard T. Ellison III, MD

Disclosures

Consult/Advisory BoardAcurx Pharmaceuticals, LLC;

Grant/Research SupportDoctors Company Foundation, Massachusetts Department of Public Health

Richard T. Ellison III, MD

Disclosures

Consult/Advisory BoardAcurx Pharmaceuticals, LLC;

Grant/Research SupportDoctors Company Foundation, Massachusetts Department of Public Health