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For nearly 3 decades, researchers have debated whether dental procedures increase the risk for prosthetic joint infection (PJI). To shed additional light on this issue, investigators conducted a prospective, case-control study involving 678 inpatients at the Mayo Clinic — 339 cases with PJI and 339 controls admitted to the orthopedic service for other reasons. Dental records were reviewed for 675 of the participants.
In a multivariate model, neither high-risk nor low-risk dental procedures performed within 6 months or 2 years of the hospital admission were associated with PJI. Moreover, the risk for PJI was similar between patients who underwent dental procedures with antibiotic prophylaxis and those who underwent similar procedures without …