Antibiotic Treatment for Staphylococcus aureus Catheter-Related Infection?

In an animal model of such infection, gentamicin performed better than vancomycin, linezolid, or ciprofloxacin.

For Staphylococcus aureus infections related to central venous catheters, the treatment of choice is to remove the device. However, this approach is not always feasible and, in selected cases, an attempt to salvage the catheter with antibiotic treatment may be preferable. What is the optimal antibiotic solution for such situations?

To find out, researchers compared four antibiotic solutions in an animal model of S. aureus catheter-related infection. They inserted intravenous catheters into rabbits and subsequently inoculated the catheters with methicillin-sensitive or methicillin-resistant S. aureus (MSSA or MRSA) strains. The animals were then treated for 24 hours, using the antibiotic-lock technique, with commercially available concentrati…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection