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Herpes zoster is a relatively common affliction among older adults and is associated with intense, sometimes long-lived pain. A live attenuated vaccine was recently shown to lower the incidence of herpes zoster and postherpetic neuralgia; however, its safety has never been described in depth. In two new studies, researchers assess adverse events in vaccinees and examine barriers to the vaccine's use.
Shingles Prevention Study Group researchers further examined data from their previously published multicenter, randomized, placebo-controlled trial of the vaccine in immunocompetent adults aged ≥60. The present and previous investigations were both partially funded by the vaccine manufacturer. Follow-up safety data were available for 37,388 indi…