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Based on the number of voluntary reports submitted to the CDC's National Notifiable Diseases Surveillance System, incidence of hepatitis A virus (HAV) infection has decreased since 1995, when an HAV vaccine was first licensed in the U.S. Now, researchers have used data from a population-based surveillance program conducted at six U.S. sites to examine recent incidence of HAV infection and its associated epidemiology.
From 2005 through 2007, 1156 cases of acute HAV disease were reported, for an overall annual incidence rate of 1.3 per 100,000 population (range by site, 0.7–2.3). Ninety-one percent of the case patients resided in urban areas, and 49% were from New York City. Among the latter group, 39% were Hispanic, and 36% were aged 15 to 39…