How Safe Is the 2009 H1N1 Influenza Vaccine?

The rate of adverse events associated with the 2009 H1N1 influenza vaccine was similar to that associated with seasonal influenza vaccines.

Concern has lingered regarding the safety of the 2009 H1N1 influenza vaccine — in particular, its risk for causing Guillain-Barré syndrome. Taking advantage of a large 5-day public gathering in China, investigators from the Beijing Centers for Disease Control and Prevention and the U.S. CDC conducted a mass vaccination program and evaluated the safety and effectiveness of the vaccine used.

The monovalent split-virion vaccine was offered to individuals aged ≥4 years. Passive surveillance for adverse events was conducted, and event severity was graded on a four-point scale. Adverse events designated as severe (grade 3 or 4) were investigated by specially trained individuals. In addition, all vaccine recipients were given diary cards to complet…

Reviewing Author

Larry M. Baddour, MD

Disclosures

RoyaltiesUpToDate, Inc. (Authorship duties)

Larry M. Baddour, MD

Disclosures

RoyaltiesUpToDate, Inc. (Authorship duties)

How Safe Is the 2009 H1N1 Influenza Vaccine?

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Reviewing Author