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Some data suggest that corticosteroids have an ameliorative effect in adults with community-acquired pneumonia (CAP), presumably because these agents downregulate inflammatory cytokines, resulting in quicker resolution of disease. In a recent retrospective cohort study, researchers examined whether corticosteroids might benefit children with CAP. They analyzed data for 20,703 CAP patients aged 1 to 18 years who were discharged from any of 38 hospitals in 2006 or 2007.
A total of 7234 (35%) patients received adjunctive corticosteroids, but the proportion varied greatly among centers (1%–51%). Across all age groups, length of stay (LOS) was shorter for children who received steroids than for those who did not. The median LOS was 3 days for all…