Management of Acute Uncomplicated Cystitis and Pyelonephritis in Healthy Women

These updated guidelines should help practitioners make appropriate treatment choices and avoid antimicrobial overuse.

Target Population: Infectious diseases specialists

Sponsoring Organizations: Infectious Diseases Society of America and European Society for Microbiology and Infectious Diseases

Type: Consensus statement

Key Points: This document updates guidelines originally published in 1999.

Nitrofurantoin is now recommended for acute uncomplicated cystitis. Other suggested antibiotics include trimethoprim-sulfamethoxazole (TMP-SMX), trimethoprim alone, and — where available — pivmecillinam or single-dose fosfomycin, although the latter may be inferior to the other regimens. Fluoroquinolones, despite their effectiveness, should not be considered as first-line agents for this indication. Oral β-lactam antibiotics other than pivmecillinam should be used with c…

Reviewing Author

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)