Hepatitis B in the U.S., 1999–2008

The rates of HBV exposure and chronic infection were significantly lower in 1999–2008 than in 1988–1994; 2-year-olds had higher immunity rates than adults.

Hepatitis B virus (HBV) is the most common cause of liver disease worldwide. HBV-associated morbidity and mortality are substantial in the U.S., even though prevalence of the virus is lower here than in some other areas. Infant immunization against HBV has been recommended since 1991, and from 2004 to 2009, about 94% of U.S. children aged 19 to 35 months received all three vaccine doses. Have the rates of immunity and chronic infection changed in recent years?

To answer this question, a researcher examined National Health and Nutrition Examination Survey (NHANES) data. From 1999 through 2008, 39,787 participants aged ≥2 years were tested for serum antibody to hepatitis B surface antigen (anti-HBs), and 37,259 individuals aged ≥6 years were t…

Reviewing Author

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

RoyaltiesUpToDate

Editorial BoardsMedical Letter

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

RoyaltiesUpToDate

Editorial BoardsMedical Letter

Hepatitis B in the U.S., 1999–2008

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Reviewing Author