Reducing Central Line–Associated Bloodstream Infections

The number of such infections in intensive care units in the U.S. has fallen markedly because of improved central line insertion and maintenance techniques.

Central line–associated bloodstream infections (CLABSIs) are common and often fatal (mortality rate, 12%–25%). In 2002, the CDC issued guidelines for the prevention of such infections. Have these guidelines had the desired effect?

To answer this question, CDC researchers — using several national data sources — estimated the number of CLABSIs among patients aged ≥1 year in intensive care units (ICUs) in the U.S. before and after publication of the guidelines. For 2001, the number of CLABSIs (after adjustment to account for a change in CLABSI definition in 2008) was estimated to be 43,000. For 2009, the number was estimated to be 18,000 — a 58% reduction.

The researchers also estimated that 37,000 CLABSIs occurred in outpatient hemodialysis fac…

Reviewing Author

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

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Editorial BoardsMedical Letter

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

RoyaltiesUpToDate

Editorial BoardsMedical Letter