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The randomized, controlled Multicenter Unsustained Tachycardia Trial tested the hypothesis that antiarrhythmic therapy (drugs and implantable defibrillators, as indicated), guided by electrophysiologic testing, reduces the risk for sudden death and cardiac arrest among patients with coronary artery disease, left ventricular systolic dysfunction, and spontaneous unsustained ventricular tachycardia. Of 704 patients with inducible, sustained ventricular tachyarrhythmia, 351 received electrophysiologically guided therapy and 353 received no antiarrhythmic therapy. Forty-five percent of the patients assigned to electrophysiologically guided therapy were discharged with antiarrhythmic drugs (class I agents, 26 percent; amiodarone, 10 percent; and…