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Left ventricular systolic dysfunction is one of the best predictors of poor outcome after MI. Although right ventricular dysfunction has been associated with reduced survival in patients with chronic left heart failure, its predictive value in asymptomatic patients with LV dysfunction after MI has been inadequately studied. In this echocardiographic substudy of 512 of the 2321 patients enrolled in the Survival and Ventricular Enlargement trial (a randomized trial of captopril vs. placebo), researchers assessed the relation between RV dysfunction and outcomes in patients with LV dysfunction (but free of heart failure) after MI. Adequate RV images were available in 416 patients. Mean follow-up was 2.6 years.
In univariate analysis, RV dysfunct…