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Depressive symptoms are common after acute MI and are associated with increased risk for adverse post-MI outcomes. However, in some affected patients, the symptoms don’t persist very long; in others, symptoms of depression surface after the MI hospitalization.
To explore the trajectory of depression in hospitalized acute-MI patients, the PREMIER investigators studied 1881 such patients who had follow-up at 1 month. According to Patient Health Questionnaire responses, 1382 patients had no depressive symptoms at hospitalization or at 1 month, 253 had depressive symptoms in the hospital but not at 1 month (transient depression), 112 had no depressive symptoms in the hospital but did at 1 month (new depression), and 134 had depressive symptoms a…