Can Correcting Mitral Regurgitation Improve the Outcome of Surgical Revascularization?

In a small study, combining mitral annuloplasty with CABG did not affect the 10-year survival rate of patients with ischemic MR.

Functional ischemic mitral regurgitation (MR) is associated with increased mortality in patients with coronary disease. However, whether annuloplasty at the time of surgical revascularization improves long-term outcomes in such patients is unclear. To explore this issue, researchers analyzed outcomes retrospectively in 390 Cleveland Clinic patients with severe (grade 3+ or 4+) MR who underwent coronary artery bypass grafting with (n=290) or without (n=100) mitral annuloplasty from 1991 to 2003.

Almost 50% of patients without annuloplasty had severe MR at 1 year, compared with about 10% of patients with annuloplasty (although at 5 years, the proportion of annuloplasty recipients with severe MR had increased to about 20%). Despite the decrease…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI