Results of a meta-analysis show small improvements and a need for more data.
To investigate the association between aerobic exercise and change in HDL levels, researchers conducted a meta-analysis of 25 randomized trials. The study was restricted to trials that included aerobic training in adults, measured HDL at baseline and at the end of the intervention, had an intervention period of at least 8 weeks, and included a nonexercise control group.
The sample sizes of the trials ranged from 9 to 200, and the total number of participants was 1404. The mean intervention period was 27.4 weeks. Overall, the quality of the studies, as assessed by the Jadad scale, was low.
The mean change in HDL was very small (2.53 mg/dL; 95% confidence interval, 1.36–3.70). Significant HDL increases were found only in programs with longer ex…
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DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association