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The prognostic importance of serum cardiac troponin levels in patients admitted to the hospital with heart failure is not well defined. Using data from an industry-sponsored registry, investigators sought to describe the association of elevated troponin levels with the risk for in-hospital death in patients hospitalized with acute decompensated heart failure. They excluded patients with a creatinine level >2.0 mg/dL because renal dysfunction may influence troponin concentration.
Of the 105,388 heart failure hospitalizations in the registry, 84,872 included a troponin measurement at initial evaluation, and 67,924 met the study enrollment criteria. The 4240 hospitalizations in which troponin levels were elevated were more likely to culminate i…