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That black patients tend to fare worse after MI than white patients do is well established. To explore why, investigators conducted a prospective cohort study involving 1849 participants in PREMIER (Prospective Registry Evaluating Myocardial Infarction: Events and Recovery) who were treated for MI at 10 hospitals between January 1, 2003, and June 28, 2004. A total of 514 (27.8%) patients were black (range, 5%–93% per site). On average, compared with white patients, black patients were younger, more likely to be female and to have non–ST-segment-elevation MI, and had more comorbidities and worse socioeconomic and psychosocial status.
In the 99% of participants for whom survival status was available, unadjusted mortality estimates were 19.9% f…