Loading...
Because fish oil has been shown to have direct electrophysiologic effects on the cell membrane as well as anti-inflammatory and autonomic-modulating properties, many clinicians are convinced of its efficacy in treating atrial fibrillation (AF), despite mixed findings from various studies. In a manufacturer-sponsored, randomized, control trial, 584 patients with paroxysmal (n=479) or persistent (n=105) AF received either 4 g/day of a prescription formulation of omega-3 fatty acids or placebo. At baseline, no participants were taking antiarrhythmic drugs, and all were free of structural heart disease and in normal sinus rhythm.
During 24 weeks of follow-up, symptomatic AF recurred in 46% of patients in the placebo group and in 52% of those in …