At 12 months, percutaneous coronary intervention and coronary artery bypass grafting produce similar improvements in symptom relief and general health status.
For patients with severe coronary artery disease who choose revascularization, deciding whether to undergo percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is often difficult. In the SYNTAX trial, bypass surgery was associated with a lower risk for the composite endpoint of death, myocardial infarction, stroke, and repeat revascularization, primarily because of a significant difference in the repeat-revascularization rate (JW Cardiol Feb 18 2009). The SYNTAX investigators now assess patient-reported outcomes, such as relief from angina and quality of life.
At 1 month, angina frequency, measured by the Seattle Angina Questionnaire (SAQ), improved in both groups, although scores on some subscales were signific…
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association