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Prescription of evidence-based medications after acute myocardial infarction (AMI) has increased substantially over the past decade. However, prescription does not ensure benefit; patients must obtain and take the drugs. In this study, sponsored by a large U.S. commercial insurer, investigators assessed full prescription coverage for evidence-based drug therapy following AMI in 5855 patients (mean age, 54; 75% men). Participants were randomized at the level of the health-plan sponsor to either full or usual coverage for angiotensin-converting–enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), beta-blockers, and statins.
Average monthly co-payments in the usual-coverage group were $13.35 for ACE inhibitors or ARBs, $12.83 for beta…