Very Low Stent Thrombosis Rates with Cobalt-Chromium Everolimus-Eluting Stents

A large meta-analysis provides sound evidence that this stent is the safest one available.

Overall rates of stent thrombosis after percutaneous coronary intervention are low (<1% at 1 year, <2% at 2 years); therefore, large sample sizes are needed to accurately estimate the relative safety of drug-eluting stents (DESs) and bare-metal stents (BMSs). To compare thrombosis rates associated with stents currently approved for use in the U.S., investigators pooled data from 49 randomized trials including 50,844 patients.

At 1 year, the risk for definite stent thrombosis was significantly lower with cobalt-chromium everolimus-eluting stents (CoCr-EESs) than with any of the other stents in the analysis (see table).The differences were significant as early as 30 days after implantation, and most remained significant between 31 days and 1 y…

Reviewing Author

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)