An Encouraging Trial of a Mesh-Covered Stent in Primary Percutaneous Coronary Intervention

Compared with other devices, a bare-metal stent with a mesh covering to trap potentially embolic material was associated with a higher rate of ST-segment resolution.

The proven benefits of primary percutaneous coronary intervention in acute myocardial infarction (MI) can be limited by suboptimal myocardial perfusion due to distal embolization. In a manufacturer-supported randomized trial, investigators tested an experimental bare-metal stent covered with a polyethylene terephthalate micronet mesh for trapping and excluding embolism-prone material to find out whether the device reduces ST-segment elevation better than commercially available stents (including both bare-metal and drug-eluting devices).

A total of 433 patients with ST-segment-elevation MI were randomized. The rate of device success was lower with the covered stent than with control stents (96% vs. 99%, P=0.03); covered-stent failures include…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI