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The development of submicrosecond pulsed lasers has led to effective treatments for a variety of epidermal and dermal pigmented disorders. Results with café-au-lait macules, however, have been variable. Two recent studies evaluated laser treatment of these lesions.
In one study, the largest series reported, 30 patients with 34 large café-au-lait macules were treated with the 510-nm pulsed dye laser at six-to-eight-week intervals with fluences of 2 to 4 J/cm2. The café-au-lait macules were completely eliminated in all patients after an average of 8.4 treatments. There were no recurrences during one year of follow-up.
In a study of 9 café-au-lait macules, half of each lesion was treated with the Q-switched Nd:YAG laser (532 nm) and half with th…